The Twins will look to continue their recent mastery of the American League East vs. the Orioles at Target Field on Saturday.
Minnesota had reeled off three straight wins against the AL East before Friday's series opening loss, 9-6.
"The last couple games against Boston, we started to play better," Twins manager Ron Gardenhire said. "We played pretty good defense throughout the whole the trip and pitched pretty good. A couple of games got away where we had chances, but to come back with your head above water against Detroit and Boston that were in first place, and Cleveland that's about as hot as anybody, that's pretty good. So we'll take it."
They'll turn to Vance Worley, who is still in search of his first victory on the season, to continue their streak.
Last time out, Worley left with the lead before the bullpen surrendered it. He gave up three earned runs on nine hits in five innings.
"I thought I had better stuff today," Worley said after the game. "I had command of both sides of the plate. I was working down, but the last couple innings, I started to elevate a little bit. But for the most part, I'm pretty happy with the outing. But it would've been nice to get a 'W.'"
Taking the mound for the Orioles will be Steve Johnson, who will be making his season debut with the club in place of the injured Miguel Gonzalez.
"My goal was to break with the team," said Johnson who started four games for Baltimore last season. "Unfortunately, it couldn't happen. I was just frustrated to not break with any team, to be stuck in extended [spring]. Had to wait and have [my right lat strain] heal, and glad to get the opportunity.
"I've only had a couple of starts, but I've felt good," said Johnson, who went 1-1 with a 4.41 ERA in three Triple-A games. "My command has been there. I haven't walked that many guys. All my stuff felt really good last time. It might be only one of the first couple of starts of the season where they're letting me go all the way, but I feel really good."
Twins: Arcia continues to swing hot bat
Rookie Oswaldo Arcia extended his career-best hit streak on Friday to eight games.
Arcia is batting .438 (14-for-32) this month, including a 2-for-5 game Friday with a run and an RBI.
"He's swinging really well," Gardenhire said. "He's very confident. It's fun watching him making adjustments as the games go along. He can hit the ball a long ways. He was chasing a few pitches, but was able to go flat-footed and shoot a couple the other way."
• The bullpen has been a strong suit for the Twins, as Minnesota's relievers entered Friday's contest with a combined 2.63 ERA, good for second in the Majors. However, they gave up six earned runs in four innings against the Orioles on Friday, raising their ERA to 3.01.
"We always talk about not overworking them, but there are going to be times when you have to," Gardenhire said. "They're going to have to step up and do a few extra things. But they've risen up and done just about everything we've thrown at them. They all have their roles and are fitting in pretty good. It seems like no matter who we send out there, they do a really nice job for us."
Orioles: Casilla may abandon switch-hitting
Orioles infielder Alexi Casilla is thinking about abandoning his switch-hitting style. He has been working on his right-handed swing, so he may stop hitting from the left side.
"They think I can stay better on the ball, on top of the ball better from my right side," Casilla said. "I don't know. Let's see. Let's see what happens. It's baseball.
"If I do good against righties from my right side -- it's a test now for me. And I'm very confident I'm going to do good."
• In four major league starts last year, Johnson was 4-0 with a 2.11 ERA, recording two quality starts.
• The Twins are 2-2 against the Orioles this season and 4-4 in their last eight meetings (since July 16, 2012).
Evan Peaslee is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.