The Cubs survived the first of a steady stream of southpaws on Monday by scoring just enough off Rockies left-hander Yohan Flande to secure a 4-1 victory.
All season long, Chicago has had the good fortune of dodging lefties for the most part, but with Colorado's all-left-handed rotation on tap, there could be some lineup changes in store.
"We've faced 18 lefties all year," Cubs manager Rick Renteria said. "Now we're in the throes of facing potentially eight or nine lefties in a row. It serves us well to use [Emilio Bonifacio] at third base so we feel comfortable with his play there."
Bonifacio got his second straight start at the hot corner on Monday over the left-handed-hitting Luis Valbuena. Bonifacio rebounded from Sunday's 0-for-4 performance by finishing 2-for-4 with two runs scored in the opener against the Rockies.
Junior Lake, who started in center field on Monday, should also see an extended run.
"He'll have a nice opportunity to get in a lot of ballgames," Renteria said of Lake. "We hope he'll have some good ballgames and something to build his confidence. We know he has skill. Maybe some of these matchups will allow him to have good performances."
But if the Cubs were only able to put up two runs against Flande and allowed him to hang around for the longest start of his Major League career, Tuesday's starter, Jorge De La Rosa, could prove to be a handful.
De La Rosa has won five straight decisions and has surrendered only five earned runs over his last 25 1/3 innings. In his most recent start, against the Nationals, he struck out 11, just one shy of his career high.
The Nationals actually got to him for eight hits in that outing, but he still held them to two runs (one earned).
"That's what the really good ones do," Rockies manager Walt Weiss said. "When they do get in trouble, they're able to wiggle out of it. Jorgy has been real good with that with us over the years."
Chicago counters with right-hander Edwin Jackson, who had to leave his last start early because of cramping in his right hand. He gave up four earned runs on seven hits over five-plus innings before exiting.
Rockies: De La Rosa hoping to stay through Trade Deadline
De La Rosa has been connected to a number of contenders -- most notably the Orioles -- as the calendar creeps closer to the July 31 non-waiver Trade Deadline, but he believes the Rockies have a bright future, and if he has the choice, he'll be in Colorado for the long run.
"I think we had enough talent to win, or be in position to win, but with all the [injuries] we've had, that's why the team went down," De La Rosa said. "But this team is going to have a lot of talent for a lot of years."
Most reports have indicated that the Rockies are leaning toward making the $14 million qualifying offer for the free-agent-to-be. De La Rosa hasn't heard that same dialogue from the team's end, but that hasn't stopped him from being successful despite the potential distraction.
"They haven't said anything to me," he said. "I just heard a lot of rumors and stuff like that. I don't pay attention to those things. I just have to go out there every five days and do my best to help this team win. I don't want those things on my mind. I just want to go out there and pitch. That's all I want."
In his seventh season with the Rockies, De La Rosa has an 11-6 record and 4.19 ERA.
Cubs: Prospects have Chicago sitting pretty
MLB.com released its updated list of Top 100 prospects on Monday, and the Cubs' booming farm system boasts the most impressive numbers.
The Cubs have the most players on the list, with eight, and according to MLB.com's point system, Chicago has 61 more points than the next highest organization, Minnesota.
Third baseman Kris Bryant is the Cubs' top-ranked prospect (No. 4 overall), and Javier Baez and Addison Russell aren't too far behind at No. 6 and No. 7, respectively.
Second baseman Arismendy Alcantara, who finished 1-for-3 with a run on Monday, made one of the biggest leaps, jumping from No. 89 earlier this season to No. 37.
• Rockies outfielder Carlos Gonzalez started on Monday for the first time since rolling his ankle before Saturday's 8-1 victory over the Pirates.
• Rockies shortstop Josh Rutledge was a late scratch from the lineup on Monday due to illness.
Cody Ulm is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.