 |
Player | Position | Former Team | New Team | Transaction date | Notes | |
| 1. | Pena, Carlos | 1B | TB | HOU | 12/17/12 | One-year contract | |
| 2. | Moore, Scott | 3B | HOU | OAK | 11/29/12 | Minor league contract | |
| 3. | Ankiel, Rick | OF | WSH | HOU | 1/17/13 | Minor league contract | |
| 4. | Buck, Travis | OF | HOU | SD | 11/28/12 | Minor league contract | |
| 5. | Sullivan, Cory | OF | HOU | PHI | 2/24/11 | Minor league contract | |
| 6. | Rodriguez, Wandy | P | HOU | HOU | 1/25/11 | Signed three-year extension | |
| 7. | Banks, Josh | RP | HOU | SF | 1/17/11 | Minor league contract | |
| 8. | Chacin, Gustavo | RP | HOU | HOU | 12/21/10 | Minor league contract | |
| 9. | Daigle, Casey | RP | HOU | SF | 12/22/10 | Minor league contract | |
| 10. | Fien, Casey | RP | DET | HOU | 11/05/10 | Minor league contract | |
| 11. | Gervacio, Sammy | RP | HOU | HOU | 12/15/10 | Minor league contract | |
| 12. | Majewski, Gary | RP | HOU | --- | --- | Minor league free agent | |
| 13. | Sampson, Chris | RP | HOU | COL | 2/16/11 | Minor league contract | |
| 14. | Veras, Jose | RP | MIL | HOU | 12/21/12 | One-year contract | |
| 15. | Bedard, Erik | SP | PIT | HOU | 1/21/13 | Minor league contract | |
| 16. | Galarraga, Armando | SP | HOU | CIN | 1/17/13 | Minor league contract | |
| 17. | Moehler, Brian | SP | HOU | --- | --- | --- | |
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